A study by scientists at Yale University School of Medicine revealed a mechanism that helps the brain protect itself from damage, according to a report on Russia Today.
اضافة اعلان
The journal JCI Insight indicated that the study found the human brain in youth has the ability to shield itself from the harmful effects of excess calcium, a key factor in neuron death associated with Alzheimer’s disease. When calcium levels rise, cells increase the production of the protein GLO1, which neutralizes toxic metabolic byproducts and reduces damage caused by calcium leakage.
Experiments on animals showed that this protective mechanism weakens with age: GLO1 activity was high in young animals but significantly decreased in older ones, making their brains more susceptible to neurodegeneration. Older animals also exhibited clear memory impairments when calcium leakage was genetically enhanced.
The study emphasizes that chronic calcium dysregulation is a major factor in cognitive decline, and that GLO1 serves as a natural compensatory mechanism. Researchers believe that maintaining the activity of this protein could open the door to new preventive strategies and provide insights into how the brain protects itself, potentially leading to treatments to prevent Alzheimer’s disease before clinical symptoms appear.
